psrwe: PS-Integrated Methods for Incorporating RWE in Clinical Studies

High-quality real-world data can be transformed into scientific real-world evidence (RWE) for regulatory and healthcare decision-making using proven analytical methods and techniques. For example, propensity score (PS) methodology can be applied to pre-select a subset of real-world data containing patients that are similar to those in the current clinical study in terms of covariates, and to stratify the selected patients together with those in the current study into more homogeneous strata. Then, methods such as the power prior approach or composite likelihood approach can be applied in each stratum to draw inference for the parameters of interest. This package provides functions that implement the PS-integrated RWE analysis methods proposed in Wang et al. (2019) <doi:10.1080/10543406.2019.1657133>, Wang et al. (2020) <doi:10.1080/10543406.2019.1684309> and Chen et al. (2020) <doi:10.1080/10543406.2020.1730877>.

Version: 3.1
Depends: methods, R (≥ 4.0), rstan (≥ 2.19.3), Rcpp (≥ 1.0.5)
Imports: parallel (≥ 3.2), cowplot (≥ 1.0.0), dplyr (≥ 0.8.5), ggplot2 (≥ 3.3.2), randomForest (≥ 4.6-14), survival, rstantools (≥ 2.1.1)
LinkingTo: BH (≥ 1.72.0-3), rstan (≥ 2.19.3), Rcpp (≥ 1.0.5), RcppEigen (≥, StanHeaders (≥ 2.21.0-5), RcppParallel (≥ 5.0.2)
Suggests: knitr, rmarkdown
Published: 2022-03-01
Author: Chenguang Wang [aut, cre], Trustees of Columbia University [cph] (tools/make_cpp.R, R/stanmodels.R), Wei-Chen Chen [aut]
Maintainer: Chenguang Wang < at>
License: GPL (≥ 3)
NeedsCompilation: yes
SystemRequirements: GNU make
Materials: NEWS
CRAN checks: psrwe results


Reference manual: psrwe.pdf
Vignettes: psrwe: Propensity Score-Integrated Methods for Incorporating Real-World Evidence in Clinical Studies


Package source: psrwe_3.1.tar.gz
Windows binaries: r-devel:, r-release:, r-oldrel:
macOS binaries: r-release (arm64): psrwe_3.1.tgz, r-oldrel (arm64): psrwe_3.1.tgz, r-release (x86_64): psrwe_3.1.tgz, r-oldrel (x86_64): psrwe_3.1.tgz
Old sources: psrwe archive


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