Sequential: Exact Sequential Analysis for Poisson and Binomial Data

Functions to calculate exact critical values, statistical power, expected time to signal, and required sample sizes for performing exact sequential analysis. All these calculations can be done for either Poisson or binomial data, for continuous or group sequential analyses, and for different types of rejection boundaries. In case of group sequential analyses, the group sizes do not have to be specified in advance and the alpha spending can be arbitrarily settled.

Version: 4.3.3
Imports: boot
Published: 2024-02-20
DOI: 10.32614/CRAN.package.Sequential
Author: Ivair Ramos Silva and Martin Kulldorff
Maintainer: Ivair Ramos Silva <ivair at>
License: GPL-2
NeedsCompilation: no
CRAN checks: Sequential results


Reference manual: Sequential.pdf


Package source: Sequential_4.3.3.tar.gz
Windows binaries: r-devel:, r-release:, r-oldrel:
macOS binaries: r-release (arm64): Sequential_4.3.3.tgz, r-oldrel (arm64): Sequential_4.3.3.tgz, r-release (x86_64): Sequential_4.3.3.tgz, r-oldrel (x86_64): Sequential_4.3.3.tgz
Old sources: Sequential archive

Reverse dependencies:

Reverse imports: SequentialDesign
Reverse suggests: EmpiricalCalibration


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